Our lab studies innovative ways to regulate the immune system to better manage and treat transplanted patients.

Our research portfolio is diverse, but our goal is singular: to redefine the boundaries of transplant medicine.

World’s First Genetically-Edited Pig Kidney Transplant into Living Recipient Performed at Massachusetts General Hospital.

Under the leadership of Leonardo V. Riella, MD, PhD, Medical Director for Kidney Transplantation, a genetically-edited pig kidney with 69 genomic edits was successfully transplanted into a living patient.

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Learn more about our kidney #xenotransplant @mgh_transplant
This short video provides an overview of the rationale, the details about the immunosuppression used, and the precautions taken in our study. Click on the second video in the video section @ https://www.leoriella.com

With tremendous joy, I share that our patient who received a gene-edited pig kidney transplant was discharged home today after removal of his dialysis access. We hope that this is a first step that will bring hope to many patients waiting for a kidney transplant #xenotransplant

Updates on ABMR, recurrent disease, cardiometabolic disease and machine perfusion strategies at the #tts2024 PGC @ttsorg @ttsecmc https://tts2024.org/program/post-graduate-course-sept-22

Congratulations to the surgeons of @MGHSurgery @LVRiella for the groundbreaking achievement .

To stay informed on the advances in xenotransplantation, check AJT's Xenobulletin page - https://www.amjtransplant.org/xenobulletin

#AJTXenoBulletin #Xenotransplantation

Landmark in Transplantationđź‘‘

Genetically-edited pig kidney with 69 genomic edits successfully transplanted into a living patient!

Congrats to Dr. Riella, Dr. Kawai, Dr. Elias and the entire team!

@LVRiella

“My deepest gratitude goes to our MGH team. For their support and expertise, I can't think of a more dedicated team and I’m grateful to be a part of it.” -Dr. Leo Riella @LVRiella, Medical Director for Kidney Transplantation, @MGHKidneys

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