1/8
🦠 Great lecture by Dr. Hohmann on Clostridium difficile infection (CDI).
A common infection with major consequences:
⚠️ ~10% all-cause 30-day mortality
Especially relevant for older & immunosuppressed patients. @mgh_transplant @KottonNelson
7/8
🌱 Microbiome restoration matters.
Encourage:
• Plant-heavy diet
• Fermented foods (eg. kefir, kraut)
Stop PPIs when possible.
For recurrent/refractory CDI → Fecal microbiota transplant (FMT)
Highly effective, but costly and not widely available.
8/8
🔑 Key takeaways of C. difficile infection:
• Minimize unnecessary antibiotics
• Interpret tests in context
• Use guideline-based therapy
• Strengthen infection control
• Consider advanced therapies for recurrence
@mgh_transplant
🚨 Our New Review Out!
Ultrasound Localization Microscopy (ULM) is reshaping how we see microvasculature at unprecedented resolution. In the kidneys, glomeruli are visualized non-invasively! Great opportunities for dx https://www.sciencedirect.com/science/article/pii/S0301562925013651?via%3Dihub @mgh_transplant @MGBKidneys
🧠🧬🩺
Great collaboration with Sylvain Bodard @univ_paris_cite & Olivier Couture @Columbia
If your transplant center does not have a structured exercise program, you can still provide recommendations📅 4-5 days/week⏱️ 30-45 min/session💪 Moderate intensity/conversational pace🚶 Walking, cycling, swimming⌚ Start 4+ weeks pre-tx. + band exercise
Consistency > Intensity
1/5
🧵Can movement alone promote transplant tolerance?
Our new @amjtransplant study suggests YES. Voluntary mobility,even without formal exercise,prolongs transplant survival via immune modulation. Even donor exercise matters
📄 https://doi.org/10.1016/j.ajt.2026.01.022
@MGHTransplant @MGBKidneys
4/5
🙏 Huge credit to our team:
Hugo Correa, Daniel Mendes, Karina Lima & @ThiagoJBorges
Special thanks to Hugo for bringing fresh insights on exercise immunology to our lab & helping launch our virtual exercise program for MGH transplant patients.
5/5
💡 Movement, by recipient or donor, can improve transplant outcomes and promote immunoregulation.
IMPLICATIONS: Consider structured exercise programs for BOTH donors and recipients. For research: Housing conditions matter.
Let’s move to tolerate!
📄 https://doi.org/10.1016/j.ajt.2026.01.022
🚀 Record-breaking year for transplants at MGB!!
In 2025, we performed 756 life-saving transplants, our highest ever.
❤️Thanks to our extraordinary team, our generous donors & our courageous patients for trusting and inspiring us every step of the way. @mgh_transplant @MGBKidneys
Great lecture by Dr Mansour @mgh_transplant on neutrophils, our most abundant circulating immune cells. Rapid responders against diverse pathogens w/multiple killing mechanisms, yet they survive only 6–24 hours. Remarkably, ~50 billion are produced daily to keep levels steady.
