Abstract Calcineurin inhibitors (CNIs) are used widely for maintenance immunosuppression in renal transplant recipients. However, their side effect profile has led researchers to attempt to find safer alternatives that can…
Belatacept and Long-Term Outcomes in Kidney Transplantation. Riella LV, Gabardi S, Azzi J. N Engl J Med. 2016 Jun 30;374(26):2599-600. doi: 10.1056/NEJMc1602859#SA4. To the Editor: We congratulate Dr. Vincenti and…
The coronary artery calcium (CAC) score is a widely recognized surrogate marker of coronary atherosclerosis, and its presence and extent are associated with increased risk of incident cardiovascular events and…
Digital Learning in Transplantation. Riella LV. Transplantation. 2016 Apr;100(4):701-702. PMID: 26998849 Physicians are lifetime learners in a world of rapidly changing information. Understanding the science of learning well and using the best available tools…
CD28 is a well-characterized co-stimulatory molecule that interacts with CD80/86 on antigen-presenting cells (APCs), comprising the critical signal 2 of T cell activation. Targeting CD28 has become an important immunosuppressive…
Accurate risk assessment is critical when evaluating potential living kidney donors. High-risk kidney APOL1 variants have been associated with end-stage renal disease of multiple causes among African Americans, though the predictive power…
Comment on Risk of end-stage renal disease following live kidney donation. Counseling potential donors to the risk of ESRD after kidney donation: glass half-full or half-empty? Allegretti AS, Yeung MY,…