Abstract The incidence of malignancy is greater in kidney transplant recipients compared to the general population, though the higher risk is not equally distributed to all types of cancers. In…
Leonardo Riella01/2017
PURPOSE OF REVIEW: The present review aims to highlight the major recent advances in transplantation with regards to basic, translational, and clinical research. RECENT FINDINGS: We describe new concepts in…
Leonardo Riella09/2016
Regulatory CD4+ Foxp3+ T cells (Tregs) are critical in controlling immunity and tolerance. Thus, preserving Treg numbers and function in transplanted patients is essential for the successful minimization of maintenance…
Leonardo Riella09/2016
Belatacept has been introduced as a promising novel immunosuppressant to the field of transplantation, especially for patients suffering from adverse effects of conventional immunosuppression such as nephrotoxicity. Analysis of rejection…
Leonardo Riella07/2016
The prevalence of Hepatitis C Virus (HCV) infection is significantly higher in patients with end-stage renal disease compared to the general population and poses important clinical challenges in patients who…
Leonardo Riella07/2016
Belatacept and Long-Term Outcomes in Kidney Transplantation. Riella LV, Gabardi S, Azzi J. N Engl J Med. 2016 Jun 30;374(26):2599-600. doi: 10.1056/NEJMc1602859#SA4. To the Editor: We congratulate Dr. Vincenti and…
Leonardo Riella07/2016
The coronary artery calcium (CAC) score is a widely recognized surrogate marker of coronary atherosclerosis, and its presence and extent are associated with increased risk of incident cardiovascular events and…
Leonardo Riella07/2016
Immune-checkpoint inhibitors are emerging as revolutionary drugs for certain malignancies. However, blocking the co-inhibitory signals may lead to immune-related adverse events, mainly in the spectrum of autoimmune diseases including colitis,…
Leonardo Riella07/2016