Acellular Hypothermic Extracorporeal Perfusion Extends Allowable Ischemia Time in a Porcine Whole Limb Replantation Model Abstract Background: One of the major challenges in traumatic amputation is the need to keep…
Leonardo Riella07/2017
Abstract Although gene-environment interactions have been investigated for many years to understand people’s susceptibility to autoimmune diseases or cancer, a role for environmental factors in modulating alloimmune responses and transplant…
Leonardo Riella07/2017
Abstract Calcineurin inhibitors (CNIs) are used widely for maintenance immunosuppression in renal transplant recipients. However, their side effect profile has led researchers to attempt to find safer alternatives that can…
Leonardo Riella07/2017
Nice debate on ASN Transplant Community about the use of IVIG for BK nephropathy. Personally, I have used IVIG in a handful of patients with refractory BK nephropathy in the past.…
Leonardo Riella02/2017
Authors Rimda Wanchoo, Leonardo V. Riella, Nupur N. Uppal, Carlos A. Lopez, Vinay Nair, Craig Devoe, Kenar D. Jhaveri Abstract The use of immune checkpoint inhibitors (ICI) in several cancers is expanding; however, their use in patients with cancer and an organ transplant…
Leonardo Riella01/2017
Abstract Constitutive proteasomes (c-20S) are ubiquitously expressed cellular proteases that degrade polyubiquitinated proteins and regulate cell functions. An isoform of proteasome, the immunoproteasome (i-20S), is highly expressed in human T…
Leonardo Riella01/2017
Abstract The incidence of malignancy is greater in kidney transplant recipients compared to the general population, though the higher risk is not equally distributed to all types of cancers. In…
Leonardo Riella01/2017
Abstract Improving long-term graft survival remains one of the critical challenges facing kidney transplantation since a great portion of kidney grafts are lost by 10years after transplantation. Understanding the causes…
Leonardo Riella12/2016