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PublicationsResearch Articles

Early Experience With Iptacopan for Recurrent IgA Nephropathy

  Kidney Med. 2025 Nov 19;8(2):101189. Authors: Al Jurdi A, Cohen Bucay A, Nissaisorakarn P, Gilligan H, Avillach CT, Klepeis VE, Smith RN, Palsson R, Safa K, Riella LV. Abstract:…
Leonardo Riella
Leonardo Riella05/2026
PublicationsResearch Articles

Combined Anti-CD20/Anti-CD38 Therapy in Posttransplant FSGS Recurrence

Transplant Direct. 2026 Jan 20;12(2):e1908. Authors: Cravedi P, Maggiore U, Mortari G, Alberici F, La Manna G, Goes N, Bouvier N, Comai G, Mehr AP, Gentile M, Palmisano A, Gessaroli…
Leonardo Riella
Leonardo Riella05/2026
PublicationsResearch Articles

Oral Tributyrin Promotes Immune Regulation and Prolongs Transplant Survival

Am J Transplant. 2026 Jan 17:S1600-6135(26)00012-2. Authors: Mendes DM, Gonçalves JIB, Liu K, Da Costa HPV, De L Correa H, Morena L, Gassen RB, Vinolo MAR, Camara NOS, de Souza…
Leonardo Riella
Leonardo Riella04/2026
NewsXenotransplantation

Seven technologies to watch in 2026

Nature’s round-up of innovations that are poised to make a splash in the year ahead. Michael Eisenstein  Nature 649, 1065-1069 (2026) From quantum computing and mRNA therapeutics to artificial-intelligence-powered climate…
Leonardo Riella
Leonardo Riella01/2026
NewsXenotransplantation

Understanding Xenotransplantation: FAQs for Patients and the Public

January 8th, 2026. Photo of Tim Andrews, our second xenorecipient, throwing the first pitch at the Red Sox Game. June 2025. What is xenotransplantation? Xenotransplantation refers to the transplantation of…
Leonardo Riella
Leonardo Riella01/2026
BlogNewsXenotransplantation

Study Reveals Unique Immune Signatures in First Living Human Pig Kidney Transplant

Boston, MA — (Jan 8th 2025)— Ourt team at Massachusetts General Hospital have published the first comprehensive immune analysis of a gene-edited pig kidney transplanted into a living human, providing…
Leonardo Riella
Leonardo Riella01/2026
PublicationsResearch Articles

Immune profiling in the first living human recipient of a gene-edited pig kidney

Nature Medicine 2026 ePub Jan 8th 2026  Authors Guilherme T. Ribas, André F. Cunha, Jonathan P. Avila, Alessia Giarraputo, Leela Morena, Karina Lima, Rodrigo B. Gassen, Jia-Yun Chen, Jia-Ren Lin,…
Leonardo Riella
Leonardo Riella01/2026
NewsXenotransplantation

NEJM Recognizes Xenotransplantation Study as a Top Article of 2025

We are honored that our publication on the first gene-edited pig kidney transplant into a living human recipient (link) has been selected by The New England Journal of Medicine as…
Leonardo Riella
Leonardo Riella01/2026
PublicationsResearch Articles

Not All Glomerular Disease Is the Same: Rethinking Exclusion in Kidney Transplant Trials

Promoting Equity in Transplant Research by Addressing the Exclusion of Patients With Glomerular Disease. Kidney Int Rep. 2025 Oct 10;10(12):4277-4280. doi: 10.1016/j.ekir.2025.09.042.  Authors: Hullekes F, Verhoeff R, Lee SA, de…
Leonardo Riella
Leonardo Riella12/2025
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