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PublicationsReviews

Beyond calcineurin inhibitors: emerging agents in kidney transplantation.

PURPOSE OF REVIEW: Despite their effectiveness, calcineurin inhibitors (CNIs) represent a major obstacle in the improvement of long-term graft survival in transplantation. The identification of new agents to implement CNI-free…
Leonardo Riella
Leonardo Riella11/2013
PublicationsReviews

T-cell co-stimulatory blockade in transplantation: two steps forward one step back!

INTRODUCTION: The concern about nephrotoxicity with calcineurin inhibitors led to the search of novel agents for immunosuppression. Based on the requirement of T-cell co-stimulatory signals to fully activated naïve T…
Leonardo Riella
Leonardo Riella11/2013
PublicationsResearch Articles

Serine protease inhibitor 6 plays a critical role in protecting murine granzyme B-producing regulatory T cells.

Regulatory T cells (Tregs) play a pivotal role in the maintenance of immune tolerance and hold great promise as cell therapy for a variety of immune-mediated diseases. However, the cellular…
Leonardo Riella
Leonardo Riella09/2013
PublicationsResearch Articles

Jagged2-signaling promotes IL-6-dependent transplant rejection.

The Notch pathway is an important intercellular signaling pathway that plays a major role in controlling cell fate. Accumulating evidence indicates that Notch and its ligands present on antigen-presenting cells…
Leonardo Riella
Leonardo Riella06/2013
PublicationsResearch Articles

B7h (ICOS-L) maintains tolerance at the fetomaternal interface.

In a successful pregnancy, the semiallogeneic fetus is not rejected by the maternal immune system, which implies tolerance mechanisms protecting fetal tissues from maternal immune attack. Here we report that…
Leonardo Riella
Leonardo Riella06/2013
PublicationsResearch Articles

Fever, dysuria and elevated serum creatinine in a kidney transplant recipient.

Fever, dysuria and elevated serum creatinine in a kidney transplant recipient. Batal I, Bijol V, Riella LV, Rennke HG. Am J Transplant. 2013 Mar;13(3):817-8.
Leonardo Riella
Leonardo Riella03/2013
Book ChaptersPublications

Nutritional Therapy in the Surgical Patient with Renal Insufficiency

Riella LV, Riella CV. “Nutritional Therapy in the Surgical Patient with Renal Insufficiency,” In: Campos AC. Chapter 66, 1st Edition, Editora Rúbio 2013; Chapter 66; Pages 619-626.
Leonardo Riella
Leonardo Riella01/2013
Book ChaptersPublications

Living donation – The gold standard

Riella LV, Chandraker A “Living donation – The gold standard,” In: Kandaswamy and Mamode Abdominal Transplantation; the State of the Art. 1st Edition, Blackwell 2013, 1st Edition; Pages 9-24.
Leonardo Riella
Leonardo Riella01/2013
Editorials/PerspectivesPublications

LITERATURE Watch: implications for transplantation.

LITERATURE Watch: implications for transplantation. Riella L, Bromberg JS. Am J Transplant. 2013 Jan;13(1):3. Download PDF
Leonardo Riella
Leonardo Riella01/2013
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