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PublicationsReviews

Antibody-mediated rejection: prevention, monitoring and treatment dilemmas.

Curr Opin Organ Transplant. 2022 Oct 1;27(5):405-414.  Authors: Rodriguez-Ramirez S, Al Jurdi A, Konvalinka A, Riella LV.  Abstract: Purpose of review: Antibody-mediated rejection (AMR) has emerged as the leading cause of late…
Leonardo Riella
Leonardo Riella01/2023
PublicationsReviews

Kidney organoids: a pioneering model for kidney diseases

Transl Res. 2022 Dec;250:1-17. Authors: Tekguc M, Gaal RCV, Uzel SGM, Gupta N, Riella LV, Lewis JA, Morizane R.  Abstract: The kidney is a vital organ that regulates the bodily…
Leonardo Riella
Leonardo Riella01/2023
PublicationsResearch Articles

Afucosylation of Anti-HLA antibody as a predictor of antibody pathogenicity in transplantation

Cell Rep Med. 2022 Nov 15;3(11):100818.  Authors: Bharadwaj P, Shrestha S, Pongracz T, Concetta C, Sharma S, Le Moine A, de Haan N, Murakami N, Riella LV, Holovska V, Wuhrer M,…
Leonardo Riella
Leonardo Riella01/2023
PublicationsResearch Articles

Molecular Characterization of Kidney Transplant Biopsies: Importance of Capillaritis and Subpathologic Rejection.

 J Am Soc Nephrol. 2022 Dec;33(12):2306-2319. Authors: Rosales IA, Mahowald GK, Tomaszewski K, Hotta K, Iwahara N, Otsuka T, Tsuji T, Takada Y, Acheampong E, Araujo-Medina M, Bruce A, Rios…
Leonardo Riella
Leonardo Riella01/2023
Editorials/PerspectivesPublications

Desensitization in transplantation: is intravenous immunoglobulin the holy grail?

 J Bras Nefrol. 2022 Dec 9. Authors: Palsson R, Riella LV. Download PDF here. Figure 1. Drugs targeting multiple steps involved in anti-HLA antibody generation, maintenance, and effector function, including B…
Leonardo Riella
Leonardo Riella01/2023
PublicationsReviews

Immune checkpoint inhibitors in kidney transplantation

Curr Opin Organ Transplant. 2023 Feb 1;28(1):46-54. Authors: Alzahrani N, Al Jurdi A, Riella LV. Abstract: Purpose of review: The development of immune checkpoint inhibitor (ICI) immunotherapy has revolutionized the treatment of…
Leonardo Riella
Leonardo Riella01/2023
PublicationsResearch Articles

Older Kidney Transplant Recipients and the Limitations of Conventional Survival Metrics

Kidney Int Rep. 2022 Aug 31;7(11):2397-2409 Authors: Vanhove T, Elias N, Safa K, Cohen-Bucay A, Schold JD, Riella LV, Gilligan H. Abstract: Introduction: The kidney transplant recipient population in the United States…
Leonardo Riella
Leonardo Riella01/2023
Editorials/PerspectivesPublications

Focal Segmental Glomerulosclerosis Recurrence Posttransplant: It Takes Two to TANGO

Kidney News August 2022 Authors: Frank Hullekes1, Rucháma Verhoeff1, Paolo Cravedi1, and Leonardo V. Riella1 Abstract: Focal segmental glomerulosclerosis (FSGS) recurrence post-transplantation represents one of the most challenging conditions causing…
Leonardo Riella
Leonardo Riella09/2022
PublicationsResearch Articles

Tixagevimab/cilgavimab pre-exposure prophylaxis is associated with lower breakthrough infection risk in vaccinated solid organ transplant recipients during the omicron wave.

Am J Transplant. 2022 Jun 21 Authors: Al Jurdi A, Morena L, Cote M, Bethea E, Azzi J, Riella LV. Abstract: The neutralizing monoclonal antibody combination of tixagevimab/cilgavimab has been shown…
Leonardo Riella
Leonardo Riella08/2022
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