Transplant Tolerance and Beyond: Key Takeaways from the Sam Strober Workshop

Transplantation. 2025 Jan 13. doi: 10.1097/TP.0000000000005311.

Stark H, Ho QY, Cross A, Alessandrini A, Bertaina A, Brennan D, Busque S, Demetris A, Devey L, Fruhwirth G, Fuchs E, Friend P, Geissler E, Guillonneau C, Hester J, Isaacs J, Jaeckel E, Kawai T, Lakkis F, Leventhal J, Levings M, Levitsky J, Lombardi G, Martinez-Llordella M, Mathew J, Moreau A, Reinke P, Riella LV, Sachs D, Fueyo AS, Schreeb K, Sykes M, Tang Q, Thomson A, Tree T, Trzonkowski P, Uchida K, Veale J, Weiner J, Wekerle T, Issa F.

The Clinical Tolerance Workshop series was established by the late Dr Sam Strober and colleagues with the goal of bringing together investigators working in the field of transplantation tolerance. For the first time, the meeting was held outside the United States. The Sixth International Workshop was run from the March 25–26, 2024 at Exeter College, University of Oxford. International world-leading scientists and clinicians gave updates on their ongoing research into tolerance induction through cell therapies and chimerism, with the goal of immunosuppression (IS) withdrawal. Invited speakers from the field of autoimmunity gave insights into the translational intersections between transplant tolerance and autoimmune regulation. Given the nature and length of these trials, regular dissemination is crucial for current investigators designing trials in the field. This report provides a comprehensive summary of these ongoing efforts.

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