Please help us evaluate the efficacy of the COVID vaccine in Transplant Patients! The emergence of SARS-CoV-2 (COVID-19) vaccines has brought great hope to all of us in the middle…
Interesting review entitled The unmapped chemical complexity of our diet by Albert-Laszlo Barabasi, Giulia Menichetti & Joseph Loscalzo Nature Food volume 1, pages33–37(2020) Abstract Our understanding of how diet affects health is limited to 150 key nutritional…
Nice debate on ASN Transplant Community about the use of IVIG for BK nephropathy. Personally, I have used IVIG in a handful of patients with refractory BK nephropathy in the past.…
The immune system has to be tightly regulated to avoid collateral damage. The discovery of regulatory cells in 1985 yielded one of the most important immunological advances in the past…
For severe or refractory rejections, thymoglobulin/ATG is commonly employed in combination with steroids and B-cell targeted therapies when indicated. However, alemtuzumab could be more effective then thymoglobulin since it depletes…
One controversial aspect in the evaluation of potential kidney recipients is the performance of stress tests for risk stratification. With the cost of stress tests ranging from U$2,500-5,000 and the long waiting…
A 31 year-old healthy male donated his kidney to his mother who had IgA nephropathy. Prior to donation, his creatinine was 1.08 mg/dl. One year after donation, his creatinine is…
Membranoproliferative glomerulonephritis on kidney biopsy. Monoclonal gammopathies generally arise from the development of an abnormal clone of B-cell lineage. The monoclonal protein can be intact immunoglogulin (often associated with free…
What are the most common type of cancers in kidney transplant recipients? Post-transplant malignancy The four most common cancers are: non-melanoma skin cancers, Kaposi’s sarcoma, kidney cancer and non-Hodgkin lymphomas. Compared…