Publications

Research Articles

Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma

Immune-checkpoint inhibitors are emerging as revolutionary drugs for certain malignancies. However, blocking the co-inhibitory signals may lead to immune-related adverse events, mainly in the spectrum of autoimmune diseases including colitis,…

Leonardo Riella07/2016

Publications Research Articles

Inflammation causes resistance to anti-CD20 mediated B cell depletion

B cells play a central role in antibody-mediated rejection and certain auto-immune diseases. However, B-cell-targeted therapy such as anti-CD20 B cell-depleting antibody(aCD20) has yielded mixed results in improving outcomes. In…

Leonardo Riella06/2016

Publications Reviews

Targeting the Notch pathway to prevent rejection.

Immune rejection is mediated by a complex interplay of cellular and humoral mechanisms. Current therapeutic strategies, which rely on global immunosuppression, can result in serious complications and are not completely…

Leonardo Riella04/2016

Editorials/Perspectives Publications

Digital Learning in Transplantation

Digital Learning in Transplantation. Riella LV. Transplantation. 2016 Apr;100(4):701-702. PMID: 26998849 Physicians are lifetime learners in a world of rapidly changing information. Understanding the science of learning well and using the best available tools…

Leonardo Riella03/2016

Book Chapters Publications

Transplant-Related Complications

Riella LV, Chandraker A. “Transplant-related Complications,” In: Li and Jevnikar. "AST Handbook of Transplant Immunology". 1st Edition, Wiley Blackwell 2015

Leonardo Riella03/2016

Book Chapters Publications

Global Considerations of Kidney Disease – Latin America

Riella LV, Riella MC. “Global Considerations of Kidney Disease – Latin America,” In: Brenner & Rector’s “The Kidney”. 9ht Edition, Saunders 2015; Chapter 77, Pages 2440-2452.

Leonardo Riella03/2016

Book Chapters Publications

Transplantation Immunobiology

Chandraker A, Riella LV, Sayegh MH. “Transplantation Immunobiology,” In: Brenner & Rector’s “The Kidney”. 9ht Edition, ; Saunders 2015; Chapter 71, Pages 2228-2250

Leonardo Riella03/2016

Publications Research Articles

Co-Dominant Role of IFN-γ- and IL-17-Producing T Cells During Rejection in Full Facial Transplant Recipients.

Facial transplantation is a life-changing procedure for patients with severe composite facial defects. However, skin is the most immunogenic of all transplants and better understanding of the immunological processes after…

Leonardo Riella01/2016

Publications Reviews

Notch and its ligands in alloimmunity and rejection.

The Notch signaling pathway is known to play a pivotal role in T- and B-cell development and fate, presenting it as an attractive therapeutic target in alloimmunity. This review provides…

Leonardo Riella01/2016

Editorials/Perspectives Publications

CD4+ CD28 Negative Cells: Armed and Dangerous.

CD28 is a well-characterized co-stimulatory molecule that interacts with CD80/86 on antigen-presenting cells (APCs), comprising the critical signal 2 of T cell activation. Targeting CD28 has become an important immunosuppressive…

Leonardo Riella01/2016

Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma

Inflammation causes resistance to anti-CD20 mediated B cell depletion

Targeting the Notch pathway to prevent rejection.

Digital Learning in Transplantation

Transplant-Related Complications

Global Considerations of Kidney Disease – Latin America

Transplantation Immunobiology

Co-Dominant Role of IFN-γ- and IL-17-Producing T Cells During Rejection in Full Facial Transplant Recipients.

Notch and its ligands in alloimmunity and rejection.

CD4+ CD28 Negative Cells: Armed and Dangerous.

Congrats to TANGO group, especially Frank Hullekes and Ruchama Verhoeff, in leading our publications from the TANGO study on recurrence of glomerular disease

Congrats to Rodrigo Gassen for his publication on the impact of ATG on follicular helper cells AJT

Congrats to Orhan Efe, Rodrigo Gassen, Thiago Borges and Ayman Al Jurdi for getting grants funded!

Upcoming Talk Nov 8th 2023: Houston Methodist

Upcoming Talk May 2024: NKF 2024 Spring Clinical Meeting, Long Beach, CA

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