Circulating B cells and plasma cells in ANCA vasculitis

Circulating B Cells, Plasma Cells, and Treg Associate with ANCA Levels in ANCA-associated Vasculitis.

Kidney Int Rep. 2020 Nov 20;6(2):496-500. doi: 10.1016/j.ekir.2020.11.016. eCollection 2021 Feb.

Authors:
Manrique J, Chan E, Hartzell S, Mon-Wei Yu S, Cantarelli C, Fernandez LF, Slon MF, Purroy C, Tassiulas I, Azzi J, Riella LV, Maggiore U, Cravedi P.
We performed acomprehensive immunophenotyping of peripheralblood mononuclear cells from a large cohort of therapy-naive AAV patients with rapidly progressive glomer-ulonephritis, including matched cohorts of patientswith noninflammatory chronic kidney disease (CKD)and healthy subjects.
Variable importance among subsets in identifying AAV patients using random forest analysis.

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