Am J Transplant. 2022 May;22(5):1496-1497.
Authors:
Maggiore U, Riella LV, Azzi J, Cravedi P
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LVR_Mortality in solid organ transplant recipients with COVID‐19 Edit AJT 2022
FIGURE 1 Comparison of COVID-19 associated mortality between SOT recipients and the general population. The plot shows how the analysis of hospital mortality may lead to misinterpretation of the comparison of COVID-19 related mortality between solid organ transplant (SOT) recipients and general population (non-SOT recipients). Hypothetical scenario in which the hospital mortality is 25% in both COVID-19 affected SOT recipients (n = 1000) and general population (n = 1000), but the hospitalization rate is four times higher in SOT recipients with respect to the general population, because SOT recipients are four times more likely to develop severe COVID-19 disease requiring hospitalization compared to the general population. After examining in-hospital mortality only, risk of death from COVID-19 would falsely appear equal in SOT recipients and general population (i.e., 25%) while deaths are in fact four times higher in SOT recipients (n = 100/1000) compared to the general population (n = 25/1000)
