Patient Selection for Initial Clinical Trials of Pig Organ Transplantation

 Transplantation. 2022 Jun 28.

Authors:

Pierson RN 3rd, Allan JS, Cooper DKC, D’Alessandro DA, Fishman JA, Kawai T, Lewis GD, Madsen JC, Markmann JF, Riella LV

Brief conclusion:

With careful selection of patients for initial clinical trials, it is likely that patients will ultimately benefit from xenotransplantation while advancing the field beyond what is possible in pig-to-nonhuman primate models.

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LVR_Patient Selection for Initial Clinical Trials of Pig Organ Transplantation 2022

FIGURE 1. Percentage survival of ESRD patients by treatment modality in 2010 (reproduced with permission from Cooper et al20), and

based on data from 2 sources (i) USRDS,21 and (ii) Orandi BJ et al.22 ESRD, end-stage renal disease.

 

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